Styrene

Styrene

SCHEMBL9763502

C=CCOC(N)=O.C=Cc1ccccc1

nearest known ligand 0.51

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.51
ALDH1A1 P00352 4/20 0.49
TSHR P16473 3/20 0.49
HSD17B10 Q99714 2/20 0.49
LMNA P02545 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
KDM4E B2RXH2 2/20 0.47
MAPT P10636 2/20 0.47
GAA P10253 1/20 0.47
MAPK1 P28482 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.44
PKM P14618 2/20 0.44
NPSR1 Q6W5P4 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2D6 P10635 1/20 0.42
HTT P42858 1/20 0.40
ALOX12 P18054 1/20 0.40
RHOA P61586 1/20 0.39
CASP1 P29466 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL11756057 0.86 CYP3A4 (0.55) CYP3A4ALDH1A1TSHRHSD17B10LMNA
Benzene SCHEMBL28209584 0.85 CYP3A4 (0.50) CYP3A4ALDH1A1TSHRHSD17B10LMNA
Styrene SCHEMBL27744788 0.84 CYP3A4 (0.53) CYP3A4ALDH1A1TSHRHSD17B10LMNA
Styrene SCHEMBL10818757 0.84 CYP3A4 (0.46) CYP3A4ALDH1A1TSHRHSD17B10LMNA
Styrene SCHEMBL1256040 0.83 MEN1 (0.53) ALDH1A1TSHRHSD17B10LMNAMEN1
Styrene SCHEMBL11873129 0.83 CYP3A4 (0.51) CYP3A4ALDH1A1TSHRHSD17B10LMNA
Styrene SCHEMBL11873141 0.83 CYP3A4 (0.51) CYP3A4ALDH1A1TSHRHSD17B10LMNA
Styrene SCHEMBL167641 0.83 CYP3A4 (0.51) CYP3A4ALDH1A1TSHRHSD17B10LMNA
Styrene SCHEMBL27482384 0.83 CYP3A4 (0.51) CYP3A4ALDH1A1TSHRHSD17B10LMNA
Styrene SCHEMBL9702693 0.81 CYP3A4 (0.80) CYP3A4ALDH1A1TSHRHSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5075384-A Air-drying, curable protective coatings comprising an allyl alcohol-styrene copolymer carbamylated by an unsaturated isocyanate, an acrylic monomer and an allyl monomer; gloss; toughness MONSANTO (US) 1991-12-24 US disclosed
US-5049623-A Solvent resistance, high gloss MONSANTO COMPANY (US) 1991-09-17 US disclosed
US-5030696-A Air- or heat-curable protective coatings of unsaturated isocyanate-modified styrene-allyl alcohol copolymer, an acrylic compound and an allyl compound; furniture; toughness MONSANTO COMPANY (US) 1991-07-09 US disclosed