Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763475 | 1.00 | SPHK1 (0.41) | SPHK1MAPTGAACYP2C9ALDH1A1 | |
| SCHEMBL9763933 | 1.00 | SPHK1 (0.41) | SPHK1MAPTGAACYP2C9ALDH1A1 | |
| SCHEMBL9764082 | 1.00 | SPHK1 (0.41) | SPHK1MAPTGAACYP2C9ALDH1A1 | |
| SCHEMBL9764199 | 1.00 | SPHK1 (0.41) | SPHK1MAPTGAACYP2C9ALDH1A1 | |
| SCHEMBL9763480 | 1.00 | SPHK1 (0.41) | SPHK1MAPTGAACYP2C9ALDH1A1 | |
| SCHEMBL9764077 | 1.00 | SPHK1 (0.41) | SPHK1MAPTGAACYP2C9ALDH1A1 | |
| SCHEMBL9763929 | 1.00 | SPHK1 (0.41) | SPHK1MAPTGAACYP2C9ALDH1A1 | |
| SCHEMBL9763525 | 1.00 | SPHK1 (0.41) | SPHK1MAPTGAACYP2C9ALDH1A1 | |
| SCHEMBL9764194 | 1.00 | SPHK1 (0.41) | SPHK1MAPTGAACYP2C9ALDH1A1 | |
| SCHEMBL8029032 | 0.99 | CYP2C9 (0.41) | SPHK1MAPTGAACYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9701905-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-07-11 | — | — | US | disclosed |
| US-20150315473-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20150299577-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2015-10-22 | — | — | US | disclosed |
| US-5032313-A | Trifluorobenzene derivative and liquid crystal composition containing the same | CHISSO CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |
| EP-0387032-A1 | Trifluorobenzene derivatives and liquid crystal compositions containing the same | Chisso Corporation (JP) | 1990-09-12 | — | — | EP | disclosed |