SCHEMBL9763729

SCHEMBL9763729

CC(C)CC(NC(=O)C(N)Cc1ccccc1)C(=O)NC(CCCNC(=N)N)C(=O)NC(C)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 15/20 0.64
NPY1R P25929 9/20 0.64
NPY5R Q15761 8/20 0.64
NPY2R P49146 5/20 0.64
KISS1R Q969F8 4/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9763738 1.00 NPY4R (0.64) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29531604 0.95 NPY4R (0.56) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL31273124 0.94 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL31222396 0.94 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30900089 0.94 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL23405249 0.93 NPY4R (0.64) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL30900192 0.93 NPY4R (0.64) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL23405252 0.93 NPY4R (0.64) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL31222365 0.92 NPY4R (0.71) NPY4RNPY1RNPY5RNPY2RKISS1R
SCHEMBL29958729 0.92 NPY4R (0.71) NPY4RNPY1RNPY5RNPY2RKISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0398944-A4 GENE EXPRESSION SYSTEM (PARTICULARLY FOR ROTAVIRUS VP7 PROTEIN) INVOLVING A FOREIGN SIGNAL PEPTIDE AND OPTIONALLY A TRANSMEMBRANE ANCHOR SEQUENCE 1991-09-11 EP disclosed
EP-0398944-A1 GENE EXPRESSION SYSTEM (PARTICULARLY FOR ROTAVIRUS VP7 PROTEIN) INVOLVING A FOREIGN SIGNAL PEPTIDE AND OPTIONALLY A TRANSMEMBRANE ANCHOR SEQUENCE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1990-11-28 EP disclosed
WO-1989007140-A1 GENE EXPRESSION SYSTEM (PARTICULARLY FOR ROTAVIRUS VP7 PROTEIN) INVOLVING A FOREIGN SIGNAL PEPTIDE AND OPTIONALLY A TRANSMEMBRANE ANCHOR SEQUENCE COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH OR (AU) 1989-08-10 WO disclosed