Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 9/20 | 0.75 |
| ▸ | FAAH | O00519 | 2/20 | 0.63 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10645500 | 0.98 | EPHX1 (0.79) | EPHX1FAAHEPHX2CASP2 | |
| SCHEMBL6283044 | 0.91 | EPHX1 (0.75) | EPHX1FAAHEPHX2CASP2 | |
| SCHEMBL25913032 | 0.89 | EPHX1 (0.79) | EPHX1FAAHEPHX2CASP2 | |
| SCHEMBL9390 | 0.89 | EPHX1 (0.95) | EPHX1EPHX2CASP2 | |
| SCHEMBL25226893 | 0.86 | EPHX1 (1.00) | EPHX1EPHX2CASP2 | |
| SCHEMBL25275041 | 0.86 | EPHX1 (1.00) | EPHX1EPHX2CASP2 | |
| SCHEMBL25225195 | 0.86 | EPHX1 (1.00) | EPHX1EPHX2CASP2 | |
| SCHEMBL25270721 | 0.86 | EPHX1 (1.00) | EPHX1EPHX2CASP2 | |
| SCHEMBL25275055 | 0.86 | EPHX1 (1.00) | EPHX1EPHX2CASP2 | |
| SCHEMBL25277850 | 0.86 | EPHX1 (1.00) | EPHX1EPHX2CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5010196-A | Acylated hexahydropyrimidines | JOHN WYETH AND BROTHERS LIMITED (GB) | 1991-04-23 | — | — | US | disclosed |
| EP-0405932-A2 | Substituted 1,3-Diaminopropanes | JOHN WYETH & BROTHER LIMITED (GB) | 1991-01-02 | — | — | EP | disclosed |