Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 16/20 | 0.67 |
| ▸ | DRD2 | P14416 | 6/20 | 0.67 |
| ▸ | DRD5 | P21918 | 4/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | THPO | P40225 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.65 |
| ▸ | GPR183 | P32249 | 1/20 | 0.65 |
| ▸ | APLNR | P35414 | 1/20 | 0.65 |
| ▸ | GLP1R | P43220 | 1/20 | 0.65 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764247 | 1.00 | DRD1 (0.67) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| SCHEMBL9764232 | 0.88 | DRD1 (0.62) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| SCHEMBL9764236 | 0.85 | DRD1 (0.70) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| SCHEMBL9764391 | 0.84 | DRD1 (0.66) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| SCHEMBL9764384 | 0.83 | DRD1 (0.67) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| SCHEMBL9764349 | 0.83 | DRD1 (0.67) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| SCHEMBL10934645 | 0.83 | DRD1 (0.64) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| SCHEMBL10744149 | 0.82 | DRD1 (0.81) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| SCHEMBL11166758 | 0.81 | DRD1 (0.69) | DRD1DRD2DRD5HSD17B10CYP1A2 | |
| SCHEMBL11103673 | 0.81 | DRD1 (0.64) | DRD1DRD2DRD5HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996202-A | 1,2,4,5 tetrahydro benzazepine-3 compounds and antipsychotic use thereof | SCHERING CORPORATION (US) | 1991-02-26 | — | — | US | disclosed |