Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.74 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.74 |
| ▸ | DRD1 | P21728 | 11/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.67 |
| ▸ | HTR2A | P28223 | 2/20 | 0.67 |
| ▸ | THPO | P40225 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.67 |
| ▸ | MTOR | P42345 | 1/20 | 0.67 |
| ▸ | DRD2 | P14416 | 4/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | DRD5 | P21918 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246721 | 0.85 | SLC6A2 (1.00) | SLC6A2SLC6A4SLC6A3DRD1DRD2 | |
| SCHEMBL9193250 | 0.84 | DRD1 (0.67) | DRD1HSD17B10HTR2ATHPOMAPK1 | |
| SCHEMBL9193257 | 0.84 | DRD1 (0.67) | DRD1HSD17B10HTR2ATHPOMAPK1 | |
| SCHEMBL14533569 | 0.84 | DRD1 (0.80) | SLC6A2SLC6A4SLC6A3DRD1HSD17B10 | |
| SCHEMBL16263409 | 0.84 | DRD1 (0.72) | DRD1HSD17B10HTR2ATHPOMAPK1 | |
| SCHEMBL2571100 | 0.83 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3DRD1HSD17B10 | |
| SCHEMBL12914280 | 0.80 | DRD1 (0.49) | SLC6A2SLC6A4SLC6A3DRD1HSD17B10 | |
| SCHEMBL11712694 | 0.80 | DRD1 (1.00) | SLC6A2SLC6A4SLC6A3DRD1HSD17B10 | |
| SCHEMBL10744149 | 0.80 | DRD1 (0.81) | DRD1HSD17B10HTR2ATHPOMAPK1 | |
| SCHEMBL9764281 | 0.80 | DRD1 (0.75) | SLC6A2SLC6A4SLC6A3DRD1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4996202-A | 1,2,4,5 tetrahydro benzazepine-3 compounds and antipsychotic use thereof | SCHERING CORPORATION (US) | 1991-02-26 | — | — | US | disclosed |