Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764705 | 0.77 | KDM4E (1.00) | KDM4ECYP1A2CYP2C19ALDH1A1HPGD | |
| SCHEMBL9764702 | 0.77 | KDM4E (1.00) | KDM4ECYP1A2CYP2C19ALDH1A1HPGD | |
| SCHEMBL3178503 | 0.76 | KDM4E (0.40) | KDM4ECYP1A2CYP2C19ALDH1A1KMT2A | |
| SCHEMBL3178497 | 0.76 | KDM4E (0.40) | KDM4ECYP1A2CYP2C19ALDH1A1KMT2A | |
| SCHEMBL2428855 | 0.76 | KDM4E (0.67) | KDM4ECYP1A2CYP2C19ALDH1A1HPGD | |
| SCHEMBL2428858 | 0.76 | KDM4E (0.67) | KDM4ECYP1A2CYP2C19ALDH1A1HPGD | |
| SCHEMBL29637243 | 0.76 | KDM4E (0.67) | KDM4ECYP1A2CYP2C19ALDH1A1HPGD | |
| SCHEMBL14478913 | 0.74 | SIRT2 (0.57) | KDM4ECYP1A2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL30380596 | 0.74 | SIRT2 (0.57) | KDM4ECYP1A2ALDH1A1HPGDL3MBTL1 | |
| SCHEMBL11626758 | 0.73 | NR4A1 (0.46) | KDM4ECYP1A2CYP2C19ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066633-A | Sensitizer for heat sensitive paper coatings | GRAPHIC CONTROLS CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |
| US-5066633-A | Sensitizer for heat sensitive paper coatings | GRAPHIC CONTROLS CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |