Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 14/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 10/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9526173 | 0.99 | SLC2A1 (0.44) | SLC2A1S1PR5S1PR4KDM4ENPC1 | |
| SCHEMBL9536894 | 0.94 | SLC2A1 (0.43) | SLC2A1S1PR5S1PR4KDM4ENPC1 | |
| SCHEMBL9537093 | 0.88 | SLC2A1 (0.51) | SLC2A1S1PR5S1PR4KDM4ENPC1 | |
| SCHEMBL9525894 | 0.83 | SLC2A1 (0.42) | SLC2A1S1PR5S1PR4CYP2A6ADRB2 | |
| Hydrochloric Acid SCHEMBL9526275 | 0.82 | SLC2A1 (0.41) | SLC2A1S1PR5S1PR4CYP2A6ADRB2 | |
| SCHEMBL9778964 | 0.81 | SLC2A1 (0.42) | SLC2A1S1PR5S1PR4KDM4ENPC1 | |
| SCHEMBL10548223 | 0.74 | CYP1A2 (0.43) | SLC2A1RAB9ACASP3SENP7SENP6 | |
| Hydrochloric Acid SCHEMBL9764686 | 0.74 | SLC2A1 (0.48) | SLC2A1MAPTCYP2A6NPBWR1KMT2A | |
| SCHEMBL9779319 | 0.74 | SLC2A1 (0.41) | SLC2A1RAB9ANPBWR1KMT2AMCHR1 | |
| SCHEMBL10546894 | 0.73 | MAPK1 (0.42) | SLC2A1KDM4EMAPTNPBWR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075455-A | Microbiocides, antitumor agents | BURROUGHS WELLCOME CO. (US) | 1991-12-24 | — | — | US | disclosed |
| US-5049581-A | Dibenzofurans having anti-tumor activity | BURROUGHS WELLCOME CO. (US) | 1991-09-17 | — | — | US | disclosed |
| US-5017600-A | Antitumor | BURROUGHS WELLCOME CO. (US) | 1991-05-21 | — | — | US | disclosed |
| US-5008286-A | Antitumor agents | BURROUGHS WELLCOME CO. (US) | 1991-04-16 | — | — | US | disclosed |
| US-4970227-A | ANTITUMOR | BURROUGHS WELLCOME CO. (US) | 1990-11-13 | — | — | US | disclosed |
| US-4965285-A | ANTITUMOR AGENTS | BURROUGHS WELLCOME CO. (US) | 1990-10-23 | — | — | US | disclosed |
| US-4866070-A | ANTITUMOR AGENT | BURROUGHS WELLCOME CO. (US) | 1989-09-12 | — | — | US | disclosed |