Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9303128 | 0.93 | TSHR (0.37) | TSHRALDH1A1TP53CYP3A4HIF1A | |
| SCHEMBL19712271 | 0.88 | TSHR (0.38) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL20485651 | 0.88 | TSHR (0.40) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL16415000 | 0.86 | TSHR (0.41) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL10429553 | 0.85 | TSHR (0.36) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| Ammonia Solution, Strong SCHEMBL28181275 | 0.84 | TSHR (0.40) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| SCHEMBL28338316 | 0.84 | TSHR (0.35) | TSHR | |
| SCHEMBL9302432 | 0.83 | TSHR (0.37) | TSHRALDH1A1TP53CYP3A4HIF1A | |
| SCHEMBL9304001 | 0.83 | TSHR (0.37) | TSHRALDH1A1TP53CYP3A4HIF1A | |
| Hydrochloric Acid SCHEMBL28821609 | 0.83 | TSHR (0.39) | TSHRALDH1A1TP53CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028638-A | Hybrid plastic filling material | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-02 | — | — | US | claimed |
| CN-115605529-B | Photochromic polydiorganosiloxane vinyl cross-linking agent | 爱尔康公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-117546077-A | Contact lens and method for manufacturing the same | 日油株式会社 | 2024-02-09 | — | — | CN | disclosed |
| CN-116867836-A | Hydrophilized polydiorganosiloxane vinyl cross-linking agent | 爱尔康公司 | 2023-10-10 | — | — | CN | disclosed |
| CN-115605529-A | Photochromic polydiorganosiloxane ethylene crosslinkers | 爱尔康公司（CH） | 2023-01-13 | — | — | CN | disclosed |
| CN-110621483-B | Silicone hydrogel contact lenses | 爱尔康公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-113480736-A | Hydrophilized polydiorganosiloxane vinyl crosslinkers and uses thereof | 爱尔康公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-108473681-B | Hydrophilized polydiorganosiloxane vinyl crosslinkers and uses thereof | 爱尔康公司 | 2021-07-20 | — | — | CN | disclosed |
| CN-110621483-A | Silicone hydrogel contact lenses | 爱尔康公司 | 2019-12-27 | — | — | CN | disclosed |