Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 3/20 | 0.69 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598202 | 0.89 | AKR1B1 (0.54) | AKR1B1UGT2B7KIF11ALDH1A1MAPT | |
| SCHEMBL11708963 | 0.86 | AKR1B1 (0.66) | AKR1B1UGT2B7MAPK14ALDH1A1MAPT | |
| SCHEMBL11707101 | 0.86 | AKR1B1 (0.66) | AKR1B1UGT2B7MAPK14ALDH1A1MAPT | |
| SCHEMBL11704205 | 0.83 | AKR1B1 (0.62) | AKR1B1UGT2B7MAPK14ALDH1A1MAPT | |
| SCHEMBL11725128 | 0.82 | AKR1B1 (0.61) | AKR1B1UGT2B7MAPK14ALDH1A1MAPT | |
| SCHEMBL11702405 | 0.82 | AKR1B1 (0.65) | AKR1B1UGT2B7MAPK14ALDH1A1MAPT | |
| SCHEMBL11270273 | 0.82 | AKR1B1 (1.00) | AKR1B1PTGS2 | |
| SCHEMBL11728387 | 0.81 | AKR1B1 (0.76) | AKR1B1UGT2B7MAPK14ALDH1A1MAPT | |
| SCHEMBL11727359 | 0.81 | AKR1B1 (0.59) | AKR1B1UGT2B7MAPK14ALDH1A1MAPT | |
| SCHEMBL11598799 | 0.81 | AKR1B1 (0.76) | AKR1B1UGT2B7MAPK14ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0272621-B1 | Method for the production of 5H-dibenzo[a,d]cyclohepten-5-ones | BASF Aktiengesellschaft (DE) | 1991-11-27 | — | — | EP | disclosed |
| US-4845302-A | Preparation of 5H-dibenzo[a,d]cyclohepten-5-ones | BASF AKTIENGSELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
| EP-0272621-A2 | Method for the production of 5H-dibenzo[a,d]cyclohepten-5-ones | BASF Aktiengesellschaft (DE) | 1988-06-29 | — | — | EP | disclosed |