Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 13/20 | 0.60 |
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GBA1 | P04062 | 3/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trimethylammonium SCHEMBL11445682 | 0.86 | SPHK2 (0.56) | SPHK2SPHK1ALDH1A1GBA1EPHX1 | |
| Methane SCHEMBL22499765 | 0.83 | SPHK2 (0.50) | SPHK2SPHK1ALDH1A1GBA1GUSB | |
| SCHEMBL11117544 | 0.81 | SPHK2 (0.69) | SPHK2SPHK1ALDH1A1GBA1GUSB | |
| SCHEMBL11114512 | 0.81 | SPHK2 (0.69) | SPHK2SPHK1ALDH1A1GBA1GUSB | |
| SCHEMBL11117820 | 0.81 | SPHK2 (0.69) | SPHK2SPHK1ALDH1A1GBA1GUSB | |
| SCHEMBL11243843 | 0.81 | SPHK2 (0.69) | SPHK2SPHK1ALDH1A1GBA1GUSB | |
| SCHEMBL11241003 | 0.81 | SPHK2 (0.69) | SPHK2SPHK1ALDH1A1GBA1GUSB | |
| SCHEMBL7596269 | 0.75 | SPHK2 (1.00) | SPHK2SPHK1 | |
| SCHEMBL7129859 | 0.75 | SPHK2 (1.00) | SPHK2SPHK1 | |
| SCHEMBL6276277 | 0.75 | SPHK2 (1.00) | SPHK2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063075-A | Amide ether derivatives as low calorie fat mimetics | NABISCO BRANDS, INC. (US) | 1991-11-05 | — | — | US | disclosed |