Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.51 |
| ▸ | WNT3A | P56704 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2124837 | 0.84 | MAPK1 (0.58) | MAPK1ALDH1A1CYP2C19POLBTSHR | |
| SCHEMBL9066195 | 0.83 | CYP1A2 (0.61) | MAPK1ALDH1A1CYP2C19POLBTSHR | |
| SCHEMBL28901970 | 0.83 | KMT2A (0.59) | MAPK1ALDH1A1TSHRCYP3A4MAPT | |
| SCHEMBL10610905 | 0.81 | MAPK1 (0.55) | MAPK1ALDH1A1CYP2C19POLBTSHR | |
| SCHEMBL10610913 | 0.81 | MAPK1 (0.55) | MAPK1ALDH1A1CYP2C19POLBTSHR | |
| SCHEMBL5059081 | 0.81 | MAPT (0.55) | MAPK1ALDH1A1CYP2C19TSHRCYP1A2 | |
| SCHEMBL1660365 | 0.80 | HSD17B2 (0.76) | MAPK1ALDH1A1CYP2C19POLBTSHR | |
| SCHEMBL30506315 | 0.80 | HSD17B2 (0.76) | MAPK1ALDH1A1CYP2C19POLBTSHR | |
| SCHEMBL11580914 | 0.80 | MAPK1 (0.54) | MAPK1ALDH1A1CYP2C19POLBTSHR | |
| SCHEMBL14601556 | 0.80 | MAPT (0.53) | MAPK1ALDH1A1CYP2C19POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063225-A | Antiarrhythmia | ROUSSEL UCLAF (FR) | 1991-11-05 | — | — | US | disclosed |