Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695790 | 0.86 | RARB (0.56) | RARBMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9817493 | 0.84 | MAPT (0.69) | RARBMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9237594 | 0.83 | RARB (0.53) | RARBMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9237597 | 0.83 | RARB (0.53) | RARBMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9282532 | 0.83 | RARB (0.53) | RARBMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9840224 | 0.83 | RARB (0.53) | RARBMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9817402 | 0.83 | RARB (0.70) | RARBMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9817633 | 0.83 | RARB (0.70) | RARBMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9817401 | 0.83 | RARB (0.70) | RARBMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9817542 | 0.83 | RARB (0.70) | RARBMAPTSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0435989-A1 | PROCESS FOR THE PREPARATION OF AROMATIC NITRILES. | MERCK PATENT GMBH (DE) | 1991-07-10 | — | — | EP | disclosed |
| WO-1991001298-A1 | PROCESS FOR THE PREPARATION OF AROMATIC NITRILES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-02-07 | — | — | WO | disclosed |