Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.47 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.47 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772169 | 0.94 | MAPT (0.55) | CCR6PAX8MAPTHTTTGM2 | |
| SCHEMBL22123600 | 0.93 | HTT (0.53) | CCR6PAX8MAPTHTTTGM2 | |
| SCHEMBL10647524 | 0.90 | CCR6 (0.51) | CCR6PAX8MAPTHTTTGM2 | |
| SCHEMBL13426204 | 0.90 | MAPT (0.51) | CCR6PAX8MAPTHTTTGM2 | |
| SCHEMBL20467679 | 0.90 | CCR6 (0.51) | CCR6PAX8MAPTHTTTGM2 | |
| SCHEMBL19732512 | 0.90 | CCR6 (0.59) | CCR6PAX8MAPTHTTTGM2 | |
| SCHEMBL9766263 | 0.89 | MAPT (0.50) | CCR6PAX8MAPTHTTTGM2 | |
| SCHEMBL4793682 | 0.89 | MAPT (0.52) | CCR6PAX8MAPTHTTTGM2 | |
| SCHEMBL34475270 | 0.88 | SMN1; SMN2 (0.50) | CCR6PAX8MAPTHTTTGM2 | |
| SCHEMBL20450596 | 0.88 | CCR6 (0.48) | CCR6PAX8MAPTHTTTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990536-A | Immunopotentiator and spergualin-related compound therefor | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-02-05 | — | — | US | disclosed |
| EP-0394684-A1 | Immunopotentiator and spergualin-related compound therefor | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1990-10-31 | — | — | EP | disclosed |