Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.50 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9160685 | 0.93 | RARB (0.56) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL9155782 | 0.93 | RARB (0.56) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL9152755 | 0.92 | RARB (0.54) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL9155798 | 0.90 | RARB (0.49) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL9152844 | 0.88 | RARB (0.54) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL9153896 | 0.88 | RARB (0.54) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL9162226 | 0.88 | NPC1 (0.45) | RARBRAB9ASMN1; SMN2NPC1HSD17B10 | |
| SCHEMBL9157300 | 0.87 | RARB (0.52) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL9875203 | 0.86 | RARB (0.41) | RARBRARARARGRAB9ASMN1; SMN2 | |
| SCHEMBL9156642 | 0.85 | RARB (0.47) | RARBRARARARGRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-A1 | PYRIDINE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |