Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9161075 | 0.92 | FFAR1 (0.59) | FFAR1CHRNB2CHRNA4HSD17B10TSHR | |
| SCHEMBL9159057 | 0.91 | FFAR1 (0.61) | FFAR1CHRNB2CHRNA4HSD17B10TSHR | |
| SCHEMBL9159025 | 0.88 | FFAR1 (0.64) | FFAR1CHRNB2CHRNA4MAPTRAB9A | |
| SCHEMBL9766627 | 0.85 | MAPT (0.43) | HSD17B10TSHRMAPTRAB9AL3MBTL1 | |
| SCHEMBL9158538 | 0.85 | FFAR1 (0.59) | FFAR1CHRNB2CHRNA4MAPTRAB9A | |
| SCHEMBL9766678 | 0.84 | HSD17B10 (0.42) | FFAR1HSD17B10TSHRMAPTRAB9A | |
| SCHEMBL10519174 | 0.83 | HSD17B10 (0.37) | FFAR1HSD17B10TSHRMAPTRAB9A | |
| SCHEMBL9874333 | 0.82 | FFAR1 (0.39) | FFAR1MAPTRAB9AL3MBTL1KDM4E | |
| SCHEMBL8436035 | 0.80 | HSD17B10 (0.56) | FFAR1HSD17B10TSHRKDM4EALDH1A1 | |
| SCHEMBL9328227 | 0.80 | HSD17B10 (0.56) | FFAR1HSD17B10TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445248-A1 | PYRIDINE DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |