Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9322570 | 0.93 | TACR1 (0.51) | TACR1CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL9323198 | 0.86 | TACR1 (0.60) | TACR1 | |
| SCHEMBL9322808 | 0.86 | TACR1 (0.60) | TACR1 | |
| SCHEMBL9325106 | 0.85 | TACR1 (0.55) | TACR1CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL9767401 | 0.85 | TACR1 (0.59) | TACR1 | |
| SCHEMBL9321890 | 0.79 | TACR1 (0.56) | TACR1 | |
| SCHEMBL9324189 | 0.78 | TACR1 (0.53) | TACR1CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL9322762 | 0.76 | TACR1 (0.51) | TACR1CHRNA7CHRNB2CHRNA4 | |
| Hydrochloric Acid SCHEMBL9323145 | 0.75 | TACR1 (0.56) | TACR1 | |
| SCHEMBL9321776 | 0.75 | TACR1 (0.52) | TACR1CHRNA7CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409931-A1 | QUINUCLIDINE THERAPEUTIC AGENTS. | PFIZER (US) | 1991-01-30 | — | — | EP | disclosed |
| WO-1990005729-A1 | QUINUCLIDINE THERAPEUTIC AGENTS | PFIZER INC. (US) | 1990-05-31 | — | — | WO | disclosed |