Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.34 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.32 |
| ▸ | RAF1 | P04049 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5120102 | 0.77 | HTR2C (0.57) | HTR2CSCN2AKDM1A | |
| SCHEMBL9020731 | 0.75 | HTR2C (0.52) | HTR2CSCN2AKDM1APGR | |
| SCHEMBL7100010 | 0.73 | HTR2C (0.43) | HTR2CSCN2A | |
| Hydrochloric Acid SCHEMBL1742023 | 0.72 | HTR2C (0.44) | HTR2CSCN2A | |
| SCHEMBL4845324 | 0.69 | HTR2C (0.41) | HTR2CSOS1ATM | |
| SCHEMBL8067555 | 0.69 | HTR2C (0.43) | HTR2CAKR1C3AKR1C2SCN2AMAPK13 | |
| SCHEMBL8541203 | 0.68 | HTR2C (0.42) | HTR2CATM | |
| SCHEMBL7435086 | 0.68 | HTR2C (0.49) | HTR2CSCN2A | |
| SCHEMBL9618625 | 0.67 | PPARG (0.45) | HTR2C | |
| Hydrochloric Acid SCHEMBL9423232 | 0.67 | PPARG (0.44) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026716-A | Method of treatment of anxiety and anxio-depressive disorders | SANOFI (FR) | 1991-06-25 | — | — | US | disclosed |