Known targets — ChEMBL curated mechanism
PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.59 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.38 |
| ▸ | ARG2 | P78540 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lysine SCHEMBL1034337 | 0.98 | GSR (0.61) | GSRGNAI3GNAO1GNAI1RNPEP | |
| Lysine SCHEMBL3739868 | 0.98 | GSR (0.61) | GSRGNAI3GNAO1GNAI1RNPEP | |
| Lysine SCHEMBL30634517 | 0.96 | GSR (0.59) | GSRGNAI3GNAO1GNAI1RNPEP | |
| Lysine SCHEMBL9767745 | 0.96 | GSR (0.59) | GSRGNAI3GNAO1GNAI1RNPEP | |
| Lysine SCHEMBL27663119 | 0.96 | GSR (0.59) | GSRGNAI3GNAO1GNAI1RNPEP | |
| Lysine SCHEMBL9767655 | 0.96 | GSR (0.59) | GSRGNAI3GNAO1GNAI1RNPEP | |
| Lysine SCHEMBL9767768 | 0.96 | GSR (0.59) | GSRGNAI3GNAO1GNAI1RNPEP | |
| Lysine SCHEMBL9767819 | 0.96 | GSR (0.59) | GSRGNAI3GNAO1GNAI1RNPEP | |
| Lysine SCHEMBL10620093 | 0.96 | GSR (0.59) | GSRGNAI3GNAO1GNAI1RNPEP | |
| Lysine SCHEMBL12470732 | 0.94 | GSR (0.57) | GSRGNAI3GNAO1GNAI1RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4021437-A1 | IMPROVING, MAINTAINING, PROTECTING AND REPAIRING TISSUE INTEGRITY, BARRIER FUNCTION AND IMMUNITY USING A COMPOSITION COMPRISING A SOURCE OF ZINC IONS | Colgate-Palmolive Company (US) | 2022-07-06 | — | — | EP | claimed |
| WO-2021203132-A1 | IMPROVING, MAINTAINING, PROTECTING AND REPAIRING TISSUE INTEGRITY, BARRIER FUNCTION AND IMMUNITY USING A COMPOSITION COMPRISING A SOURCE OF ZINC IONS | COLGATE-PALMOLIVE COMPANY (US) | 2021-10-07 | — | — | WO | claimed |
| US-20210308028-A1 | Compositions and Methods for Maintaining and Protecting Tissue Integrity and Barrier Function | COLGATE-PALMOLIVE COMPANY (US) | 2021-10-07 | — | — | US | claimed |
| US-20160296437-A1 | ORAL CARE ZINC COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2016-10-13 | — | — | US | claimed |
| EP-3076921-A1 | ORAL CARE ZINC COMPOSITIONS | Colgate-Palmolive Company (US) | 2016-10-12 | — | — | EP | claimed |
| WO-2015084314-A1 | ORAL CARE ZINC COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2015-06-11 | — | — | WO | claimed |
| EP-4021437-A1 | IMPROVING, MAINTAINING, PROTECTING AND REPAIRING TISSUE INTEGRITY, BARRIER FUNCTION AND IMMUNITY USING A COMPOSITION COMPRISING A SOURCE OF ZINC IONS | Colgate-Palmolive Company (US) | 2022-07-06 | — | — | EP | disclosed |
| WO-2021203132-A1 | IMPROVING, MAINTAINING, PROTECTING AND REPAIRING TISSUE INTEGRITY, BARRIER FUNCTION AND IMMUNITY USING A COMPOSITION COMPRISING A SOURCE OF ZINC IONS | COLGATE-PALMOLIVE COMPANY (US) | 2021-10-07 | — | — | WO | disclosed |
| US-20210308028-A1 | Compositions and Methods for Maintaining and Protecting Tissue Integrity and Barrier Function | COLGATE-PALMOLIVE COMPANY (US) | 2021-10-07 | — | — | US | disclosed |
| CN-111214388-A | Oral care zinc compositions | 高露洁-棕榄公司 | 2020-06-02 | — | — | CN | disclosed |
| EP-3076921-B1 | ORAL CARE ZINC COMPOSITIONS | COLGATE PALMOLIVE CO (US) | 2020-03-04 | — | — | EP | disclosed |
| US-9943473-B2 | Zinc lysine halide complex | COLGATE-PALMOLIVE COMPANY (US) | 2018-04-17 | — | — | US | disclosed |
| US-9925130-B2 | Composition with zinc amino acid/trimethylglycine halide precursors | COLGATE-PALMOLIVE COMPANY (US) | 2018-03-27 | — | — | US | disclosed |
| US-20150328095-A1 | COMPOSITION WITH ZINC AMINO ACID/TRIMETHYLGLYCINE HALIDE PRECURSORS | COLGATE-PALMOLIVE COMPANY (US) | 2015-11-19 | — | — | US | disclosed |
| EP-2934439-A1 | COMPOSITION WITH ZINC AMINO ACID/TRIMETHYLGLYCINE HALIDE PRECURSORS | Colgate-Palmolive Company (US) | 2015-10-28 | — | — | EP | disclosed |
| EP-2934438-A1 | ZINC AMINO ACID/TRIMETHYLGLYCINE HALIDE | Colgate-Palmolive Company (US) | 2015-10-28 | — | — | EP | disclosed |
| WO-2015084314-A1 | ORAL CARE ZINC COMPOSITIONS | COLGATE-PALMOLIVE COMPANY (US) | 2015-06-11 | — | — | WO | disclosed |
| WO-2014098814-A1 | COMPOSITION WITH ZINC AMINO ACID/TRIMETHYLGLYCINE HALIDE PRECURSORS | COLGATE-PALMOLIVE COMPANY (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014098813-A1 | ZINC AMINO ACID/TRIMETHYLGLYCINE HALIDE | COLGATE-PALMOLIVE COMPANY (US) | 2014-06-26 | — | — | WO | disclosed |
| US-5061815-A | Dietary supplementation | ZINPRO CORPORATION (US) | 1991-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150328095-A1 | COMPOSITION WITH ZINC AMINO ACID/TRIMETHYLGLYCINE HALIDE PRECURSORS | ZFX, SLC39A3, SLC39A11 | GSR 969/4885GNAI3 2490/4885GNAO1 2555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.