Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 13/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.31 |
| ▸ | TUBB | P07437 | 2/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.31 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.31 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.31 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.31 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9719870 | 0.77 | PTAFR (0.48) | PTAFRBPTF | |
| SCHEMBL9719869 | 0.77 | PTAFR (0.48) | PTAFRBPTF | |
| SCHEMBL9859193 | 0.69 | PTAFR (0.74) | PTAFR | |
| SCHEMBL9859198 | 0.69 | PTAFR (0.74) | PTAFR | |
| SCHEMBL9859211 | 0.69 | PTAFR (0.74) | PTAFR | |
| SCHEMBL9719040 | 0.64 | MAPT (0.63) | PTAFRMAPTTUBB4ATUBBTUBA3C | |
| SCHEMBL9859486 | 0.63 | PTAFR (0.86) | PTAFR | |
| SCHEMBL9859932 | 0.63 | PTAFR (0.86) | PTAFR | |
| SCHEMBL9859944 | 0.63 | PTAFR (0.86) | PTAFR | |
| SCHEMBL9691737 | 0.61 | PTAFR (0.75) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047420-A | Platelet activating factor | MERCK & CO., INC. (US) | 1991-09-10 | — | — | US | disclosed |