Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.73 |
| ▸ | TTR | P02766 | 1/20 | 0.73 |
| ▸ | PPOX | P50336 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768735 | 0.89 | TDP1 (0.71) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11277011 | 0.88 | TDP1 (0.60) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11500024 | 0.88 | TDP1 (0.67) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11322256 | 0.87 | MEN1 (0.66) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10995107 | 0.87 | TDP1 (0.74) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11124317 | 0.87 | KMT2A (0.77) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11113930 | 0.86 | MEN1 (0.65) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL10907643 | 0.86 | TDP1 (0.67) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11068222 | 0.86 | TDP1 (0.72) | MEN1KMT2ATDP1TTRPPOX | |
| SCHEMBL11109595 | 0.86 | MEN1 (0.69) | MEN1KMT2ATDP1TTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073188-A | Herbicidal amides of 4-trifluoromethyl-3'-carboxyl-4'-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| US-4937381-A | Herbicidal amides of 4-trifluoromethyl-3'-carboxyl-4'-nitro-diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1990-06-26 | — | — | US | disclosed |
| EP-0027837-B1 | SUBSTITUTED DIPHENYL ETHERS HAVING UTILITY AS HERBICIDES | ROHM AND HAAS COMPANY (US) | 1984-08-08 | — | — | EP | disclosed |
| EP-0019388-B1 | PREPARATION OF TRIFLUOROMETHYL-SUBSTITUTED PHENOLS AND PHENATES AND THE PREPARATION, FROM THESE PHENOLS AND PHENATES, OF NITRO- AND TRIFLUOROMETHYL-SUBSTITUTED DIPHENYL ETHERS | ROHM AND HAAS COMPANY (US) | 1983-03-23 | — | — | EP | disclosed |
| US-4262152-A | REACTION OF TRIFLUOROMETHYLHALOBENZENE WITH A BASE IN A COSOLVENT SYSTEM TO YIELD A TRIFLUOROMETHYL PHENOLATE | ROHM AND HAAS COMPANY (US) | 1981-04-14 | — | — | US | disclosed |
| US-4259510-A | TREATING A TRIFLUOROMETHYLHALOBENZENE WITH A HYDROXIDE FOLLOWED BY ETHERIFICATION WITH A HALONITROBENZENE | ROHM AND HAAS COMPANY | 1981-03-31 | — | — | US | disclosed |
| EP-0019388-A1 | Preparation of trifluoromethyl-substituted phenols and phenates and the preparation, from these phenols and phenates, of nitro- and trifluoromethyl-substituted diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1980-11-26 | — | — | EP | disclosed |