Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | TTR | P02766 | 1/20 | 0.76 |
| ▸ | PPOX | P50336 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PYGL | P06737 | 1/20 | 0.44 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9768714 | 0.91 | TDP1 (0.77) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10441016 | 0.90 | TDP1 (0.78) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10441014 | 0.90 | TDP1 (0.78) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11322260 | 0.89 | TDP1 (0.69) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10991967 | 0.89 | TDP1 (0.77) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL21653869 | 0.89 | TDP1 (0.80) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL9768703 | 0.88 | TDP1 (0.73) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10996421 | 0.88 | TDP1 (0.73) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11298723 | 0.88 | TDP1 (0.79) | TDP1MEN1KMT2ATTRPPOX | |
| Acifluorfen-Methyl SCHEMBL39092 | 0.88 | MEN1 (0.78) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073188-A | Herbicidal amides of 4-trifluoromethyl-3'-carboxyl-4'-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0027837-B1 | SUBSTITUTED DIPHENYL ETHERS HAVING UTILITY AS HERBICIDES | ROHM AND HAAS COMPANY (US) | 1984-08-08 | — | — | EP | disclosed |