Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | TTR | P02766 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | PPOX | P50336 | 1/20 | 0.72 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.51 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.51 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | DTYMK | P23919 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11147168 | 1.00 | MEN1 (0.72) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL6567283 | 0.88 | MEN1 (0.68) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL11126332 | 0.88 | TDP1 (0.58) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL11124081 | 0.88 | TDP1 (0.58) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL10786867 | 0.87 | TDP1 (0.81) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL11023426 | 0.86 | TDP1 (0.58) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL10673512 | 0.85 | TDP1 (0.78) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL10669894 | 0.85 | TDP1 (0.78) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL38930 | 0.85 | TDP1 (0.78) | MEN1KMT2ATTRTDP1PPOX | |
| SCHEMBL10668736 | 0.85 | TDP1 (0.64) | MEN1KMT2ATTRTDP1PPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073188-A | Herbicidal amides of 4-trifluoromethyl-3'-carboxyl-4'-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| US-4937381-A | Herbicidal amides of 4-trifluoromethyl-3'-carboxyl-4'-nitro-diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1990-06-26 | — | — | US | disclosed |
| US-4626275-A | Certain 5-(pyridyl-2'-oxy)-2-nitrobenzoic acid ester derivatives herbicidal compositions containing same and their herbicidal use | CIBA-GEIGY CORPORATION (US) | 1986-12-02 | — | — | US | disclosed |
| US-4618359-A | 3-TETRAHYDROFURYL 2-NITRO-5(2-CHLORO-4-TRIFLOROMETHYLPHENOXY)BENZOATE | SANDOZ LTD. (CH) | 1986-10-21 | — | — | US | disclosed |
| US-4427441-A | HEABICIDES | VELSICOL CHEMICAL CORPORATION (US) | 1984-01-24 | — | — | US | disclosed |
| US-4420328-A | Derivatives of 5-(pyridyl-2-oxy)-2-nitrobenzoic acid, and herbicidal compositions containing them | CIBA-GEIGY CORPORATION (US) | 1983-12-13 | — | — | US | disclosed |
| US-4395570-A | CONDENSATION OF 4-TRIFLUOROMETHYLPHENOL WITH 1-HAL-4-SUBSTITUTED-4-NITROBENZENE, THEN HALOGENATION | ROHM AND HAAS COMPANY (US) | 1983-07-26 | — | — | US | disclosed |
| US-4326880-A | HERBICIDE | CIBA-GEIGY CORPORATION (US) | 1982-04-27 | — | — | US | disclosed |
| US-4209318-A | Herbicidal esters of 4-trifluoromethyl-3-carboxamido-4-nitro diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1980-06-24 | — | — | US | disclosed |