Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | PPOX | P50336 | 1/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CCR6 | P51684 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10802363 | 0.94 | TDP1 (0.52) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11296069 | 0.89 | TDP1 (0.55) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11386973 | 0.88 | TDP1 (0.56) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10671105 | 0.86 | TDP1 (0.54) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10552727 | 0.85 | TDP1 (0.76) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10553434 | 0.85 | TDP1 (0.62) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11474498 | 0.84 | TDP1 (0.55) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11298356 | 0.84 | TDP1 (0.51) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10775899 | 0.84 | KMT2A (0.52) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10661295 | 0.84 | TDP1 (0.56) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073188-A | Herbicidal amides of 4-trifluoromethyl-3'-carboxyl-4'-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| US-4937381-A | Herbicidal amides of 4-trifluoromethyl-3'-carboxyl-4'-nitro-diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1990-06-26 | — | — | US | disclosed |