Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | TTR | P02766 | 1/20 | 0.61 |
| ▸ | PPOX | P50336 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | CCR6 | P51684 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10441014 | 0.88 | TDP1 (0.78) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10441016 | 0.88 | TDP1 (0.78) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL38930 | 0.88 | TDP1 (0.78) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10675557 | 0.87 | TDP1 (0.61) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10673393 | 0.87 | TDP1 (0.56) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL28965472 | 0.87 | TDP1 (0.76) | TDP1MEN1KMT2ATTRPPOX | |
| Hydrochloric Acid SCHEMBL27554382 | 0.87 | TDP1 (0.76) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL1902740 | 0.87 | TDP1 (0.76) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL15441532 | 0.87 | TDP1 (0.76) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11386973 | 0.86 | TDP1 (0.56) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073188-A | Herbicidal amides of 4-trifluoromethyl-3'-carboxyl-4'-nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1991-12-17 | — | — | US | disclosed |
| US-4937381-A | Herbicidal amides of 4-trifluoromethyl-3'-carboxyl-4'-nitro-diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1990-06-26 | — | — | US | disclosed |