Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | MEN1 | O00255 | 4/20 | 0.81 |
| ▸ | THRB | P10828 | 3/20 | 0.81 |
| ▸ | RECQL | P46063 | 2/20 | 0.81 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.81 |
| ▸ | POLB | P06746 | 2/20 | 0.81 |
| ▸ | USP2 | O75604 | 1/20 | 0.81 |
| ▸ | PKM | P14618 | 1/20 | 0.81 |
| ▸ | APEX1 | P27695 | 1/20 | 0.81 |
| ▸ | BLM | P54132 | 1/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL107833 | 0.92 | KMT2A (0.95) | TDP1KMT2AMAPTMEN1THRB | |
| SCHEMBL715406 | 0.92 | KDM4E (0.65) | TDP1KMT2AMAPTMEN1THRB | |
| Ammonia Solution, Strong SCHEMBL6030557 | 0.90 | KDM4E (0.63) | TDP1KMT2AMAPTMEN1THRB | |
| SCHEMBL6030346 | 0.90 | KDM4E (0.63) | TDP1KMT2AMAPTMEN1THRB | |
| Hydrochloric Acid SCHEMBL864766 | 0.90 | KMT2A (1.00) | TDP1KMT2AMAPTMEN1THRB | |
| Trimethylammonium SCHEMBL6742487 | 0.84 | KDM4E (0.57) | TDP1KMT2AMAPTMEN1THRB | |
| Aminobenzoic Acid SCHEMBL3357490 | 0.82 | KDM4E (0.55) | TDP1KMT2AMAPTMEN1THRB | |
| SCHEMBL8716259 | 0.82 | MAPT (0.55) | TDP1KMT2AMAPTMEN1THRB | |
| SCHEMBL29091434 | 0.82 | TDP1 (0.70) | TDP1KMT2AMAPTMEN1THRB | |
| SCHEMBL28487397 | 0.81 | KMT2A (0.75) | TDP1KMT2AMAPTMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021558-A | Color strength, fastness | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |