⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15249598 | 0.77 | — | — | |
| SCHEMBL20843958 | 0.74 | — | — | |
| SCHEMBL17428950 | 0.72 | — | — | |
| SCHEMBL31337815 | 0.72 | — | — | |
| SCHEMBL1901529 | 0.69 | — | — | |
| SCHEMBL9769024 | 0.65 | — | — | |
| SCHEMBL18876351 | 0.62 | NQO1 (0.32) | — | |
| SCHEMBL18876389 | 0.62 | CYP3A4 (0.32) | — | |
| SCHEMBL18876374 | 0.61 | NQO1 (0.36) | — | |
| SCHEMBL24791806 | 0.61 | MAOB (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083779-B | A kind of synthetic method of 2,5- furandicarboxylic acids | 绵阳高新区达高特科技有限公司 | 2018-08-17 | — | — | CN | claimed |
| CN-106083779-A | A kind of synthetic method of 2,5 furandicarboxylic acids | 绵阳高新区达高特科技有限公司 | 2016-11-09 | — | — | CN | claimed |
| WO-2023110138-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023275337-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-01-05 | — | — | WO | disclosed |
| WO-2023275333-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-01-05 | — | — | WO | disclosed |
| CN-106083779-B | A kind of synthetic method of 2,5- furandicarboxylic acids | 绵阳高新区达高特科技有限公司 | 2018-08-17 | — | — | CN | disclosed |
| EP-3154973-B1 | TRICYCLIC COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | BRISTOL MYERS SQUIBB CO (US) | 2018-03-21 | — | — | EP | disclosed |
| US-9708323-B2 | Tricyclic compounds as alpha-7 nicotinic acetylcholine receptor ligands | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-07-18 | — | — | US | disclosed |
| US-20170137425-A1 | TRICYCLIC COMPOUNDS AS ALPHA-7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-18 | — | — | US | disclosed |
| CN-106083779-A | A kind of synthetic method of 2,5 furandicarboxylic acids | 绵阳高新区达高特科技有限公司 | 2016-11-09 | — | — | CN | disclosed |
| US-9376430-B2 | Broad spectrum benzothiophene-nitrothiazolide and other antimicrobials | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2016-06-28 | — | — | US | disclosed |
| US-8232407-B2 | Nitrogenous heterocyclic compounds with insecticidal activity, and the preparation and use thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2012-07-31 | — | — | US | disclosed |
| US-8232407-B2 | Nitrogenous heterocyclic compounds with insecticidal activity, and the preparation and use thereof | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2012-07-31 | — | — | US | disclosed |
| US-20110144321-A1 | SYNTHETIC INTERMEDIATES AND PROCESSES | BIOCRYST PHARMACEUTICALS, INC. (US) | 2011-06-16 | — | — | US | disclosed |
| EP-2281812-A1 | NITROGENOUS HETEROCYCLIC COMPOUND WITH INSECTICIDAL ACTIVITY AND ITS PREPARATION AND USE | East China University of Science and Technology (CN) | 2011-02-09 | — | — | EP | disclosed |
| US-20100298346-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS WITH INSECTICIDAL ACTIVITY, AND THE PREPARATION AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-11-25 | — | — | US | disclosed |
| US-20100298346-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS WITH INSECTICIDAL ACTIVITY, AND THE PREPARATION AND USE THEREOF | EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2010-11-25 | — | — | US | disclosed |
| CN-101289431-A | Thiazoline multithioether compounds with sterilization activity, synthetic method and applications | UNIV SCIENCE AND TECHNOLOGY LI (CN) | 2008-10-22 | — | — | CN | disclosed |
| US-4992534-A | Anticarcinogenic agents with better water solubility, low toxicity, absorption and stability | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-12 | — | — | US | disclosed |
| EP-0303269-A2 | 2'-Deoxy-5-fluorouridine derivatives, process for preparing the same and the use thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-02-15 | — | — | EP | disclosed |