⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isobutane SCHEMBL11848516 | 0.96 | — | — | |
| Butane SCHEMBL11859319 | 0.86 | — | — | |
| Water SCHEMBL27509838 | 0.70 | — | — | |
| Water SCHEMBL28118224 | 0.70 | TSHR (1.00) | — | |
| SCHEMBL14877 | 0.70 | — | — | |
| SCHEMBL9492341 | 0.70 | TSHR (1.00) | — | |
| Water SCHEMBL8933153 | 0.68 | — | — | |
| SCHEMBL14539516 | 0.68 | TSHR (0.39) | — | |
| SCHEMBL31351832 | 0.67 | — | — | |
| SCHEMBL21424233 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0526588-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK AS (DK) | 1994-03-09 | — | — | EP | claimed |
| EP-0526588-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE. | NOVO NORDISK AS (DK) | 1993-02-10 | — | — | EP | claimed |
| WO-1991016325-A1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1991-10-31 | — | — | WO | claimed |
| US-4168244-A | CONJUGATED DIOLEFINS TO HIGH MOLECULAR WEIGHT STEREOREGULAR POLYMERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-09-18 | — | — | US | claimed |
| US-4051129-A | REACTION OF BENZYLIDENIMINO GROUP WITH HYDRAZINE, AMIDATION | SANKYO COMPANY LIMITED (JA) | 1977-09-27 | — | — | US | claimed |
| US-4048418-A | Method of polymerization of conjugated diolefins using iron catalysts and nitrogen ligands | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-09-13 | — | — | US | claimed |
| JP-58198460-A | — | — | None | — | — | JP | disclosed |
| JP-6145138-A | — | — | None | — | — | JP | disclosed |
| US-20250368654-A1 | HETEROCYCLIC INHIBITORS OF ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2025-12-04 | — | — | US | disclosed |
| CN-111655258-B | Compositions for cryopreservation and methods of use thereof | 常青树生物科学公司 | 2025-03-21 | — | — | CN | disclosed |
| US-20240376113-A1 | HETEROCYCLIC INHIBITORS OF ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2024-11-14 | — | — | US | disclosed |
| US-12091412-B2 | Heterocyclic inhibitors of ENPP1 | VOLASTRA THERAPEUTICS, INC. (US) | 2024-09-17 | — | — | US | disclosed |
| CN-118044519-A | Molecules having pesticidal utility, and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2024-05-17 | — | — | CN | disclosed |
| US-4180568-A | CONTROL OF POWDERY MILDEW ON GRAPES | ELI LILLY AND COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4168244-A | CONJUGATED DIOLEFINS TO HIGH MOLECULAR WEIGHT STEREOREGULAR POLYMERS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1979-09-18 | — | — | US | disclosed |
| US-4163832-A | Polythioethers formed by anionic ring opening of episulfides | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-08-07 | — | — | US | disclosed |
| US-4091096-A | Dinitroanilines for the control of phytopathogens | ELI LILLY AND COMPANY (US) | 1978-05-23 | — | — | US | disclosed |
| US-4051129-A | REACTION OF BENZYLIDENIMINO GROUP WITH HYDRAZINE, AMIDATION | SANKYO COMPANY LIMITED (JA) | 1977-09-27 | — | — | US | disclosed |
| US-4048418-A | Method of polymerization of conjugated diolefins using iron catalysts and nitrogen ligands | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4045466-A | GRAPE DOWNY MILDEW-FUNGICIDE | ELI LILLY AND COMPANY (US) | 1977-08-30 | — | — | US | disclosed |