Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4921789 | 0.72 | CYP1A2 (0.46) | KDM4ELMNACYP1A2KMT2AALDH1A1 | |
| SCHEMBL4921787 | 0.70 | CYP1A2 (0.41) | KDM4ELMNACYP1A2KMT2AALDH1A1 | |
| SCHEMBL352579 | 0.69 | CYP1A2 (0.54) | KDM4ECYP1A2KMT2ANPC1MAPT | |
| SCHEMBL16796251 | 0.68 | KMT2A (0.47) | KDM4ECYP1A2KMT2ANPC1MAPT | |
| SCHEMBL12396913 | 0.67 | CYP1A2 (0.49) | KDM4ELMNACYP1A2KMT2ANPC1 | |
| SCHEMBL124262 | 0.67 | CA12 (0.50) | KDM4ELMNAPKMCYP1A2KMT2A | |
| SCHEMBL31084629 | 0.67 | PDE4D (0.44) | KDM4ELMNAPKMCYP1A2KMT2A | |
| SCHEMBL463064 | 0.67 | KDM4E (0.42) | KDM4ELMNAPKMCYP1A2KMT2A | |
| SCHEMBL489524 | 0.66 | TSHR (0.52) | KDM4ELMNACYP1A2NPC1RAB9A | |
| SCHEMBL978908 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5057398-A | Improved photosensitivity | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-15 | — | — | US | disclosed |