Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.33 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10401867 | 0.91 | TSHR (0.34) | SMN1; SMN2POLBMAPTPDE3ASLC22A6 | |
| SCHEMBL9770262 | 0.90 | POLB (0.35) | SMN1; SMN2POLBMAPTPDE3ASLC22A6 | |
| SCHEMBL8626068 | 0.84 | SMN1; SMN2 (0.33) | SMN1; SMN2POLBMAPTPDE3ASLC22A6 | |
| SCHEMBL10596819 | 0.83 | SMN1; SMN2 (0.33) | SMN1; SMN2POLB | |
| SCHEMBL10817522 | 0.83 | POLB (0.34) | SMN1; SMN2POLBMAPTPDE3ASLC22A6 | |
| SCHEMBL10404206 | 0.82 | MAPT (0.36) | SMN1; SMN2POLBMAPTPDE3ASLC22A6 | |
| SCHEMBL10493331 | 0.81 | MAPT (0.32) | MAPTPDE3ASLC22A6SLC22A8SLC22A11 | |
| SCHEMBL8113253 | 0.81 | MAPT (0.43) | SMN1; SMN2POLBMAPTPDE3ASLC22A6 | |
| SCHEMBL3731768 | 0.81 | MAPT (0.43) | SMN1; SMN2POLBMAPTPDE3ASLC22A6 | |
| SCHEMBL10933958 | 0.80 | DRD1 (0.34) | SMN1; SMN2POLBMAPTPDE3ASLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028427-A | Antibiotic | BEECHAM GROUP P.L.C. (GB) | 1991-07-02 | — | — | US | disclosed |
| EP-0071395-B1 | BETA-LACTAM ANTIBACTERIAL AGENTS | BEECHAM GROUP PLC (GB) | 1988-08-10 | — | — | EP | disclosed |