Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | FNTA | P49354 | 4/20 | 0.61 |
| ▸ | FNTB | P49356 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.52 |
| ▸ | SQLE | Q14534 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770441 | 1.00 | NR1I2 (0.62) | NR1I2LMNAPGRFNTAFNTB | |
| SCHEMBL10404491 | 1.00 | NR1I2 (0.62) | NR1I2LMNAPGRFNTAFNTB | |
| SCHEMBL10405284 | 1.00 | NR1I2 (0.62) | NR1I2LMNAPGRFNTAFNTB | |
| SCHEMBL15820994 | 0.96 | NR1I2 (0.67) | NR1I2LMNAPGRFNTAFNTB | |
| SCHEMBL372460 | 0.96 | NR1I2 (0.67) | NR1I2LMNAPGRFNTAFNTB | |
| SCHEMBL23722461 | 0.96 | NR1I2 (0.67) | NR1I2LMNAPGRFNTAFNTB | |
| SCHEMBL15821563 | 0.96 | NR1I2 (0.67) | NR1I2LMNAPGRFNTAFNTB | |
| SCHEMBL23722462 | 0.96 | NR1I2 (0.67) | NR1I2LMNAPGRFNTAFNTB | |
| SCHEMBL372459 | 0.96 | NR1I2 (0.67) | NR1I2LMNAPGRFNTAFNTB | |
| SCHEMBL15821218 | 0.96 | NR1I2 (0.67) | NR1I2LMNAPGRFNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57031615-A | — | — | None | — | — | JP | disclosed |
| JP-57181012-A | — | — | None | — | — | JP | disclosed |
| US-4988732-A | Antitumor agents, skin disorders | EISAI CO., LTD. (JP) | 1991-01-29 | — | — | US | disclosed |
| US-4954525-A | POLYPRENYL ACID, AMIDE OR KETONE | EISAI CO., LTD. (JP) | 1990-09-04 | — | — | US | disclosed |
| US-4917829-A | ANTICANCER AGENT | EISAI CO., LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| US-4835183-A | Method of treating cancerous and precancerous conditions | EISAI CO., LTD. (JP) | 1989-05-30 | — | — | US | disclosed |
| US-4655973-A | ANTICANCER AGENTS | EISAI CO., LTD. (JP) | 1987-04-07 | — | — | US | disclosed |
| EP-0175171-A2 | Use of 3,7,11,15-tetramethyl-2,4,6,10,14-hexadecapentaenoic acid for enhancing the effect of anti-tumour agents | Eisai Co., Ltd. (JP) | 1986-03-26 | — | — | EP | disclosed |
| EP-0107188-B1 | A PHARMACEUTICAL COMPOSITION AND THE USE THEREOF FOR THE TREATMENT OF INFLAMMATION | Eisai Co., Ltd. (JP) | 1986-02-26 | — | — | EP | disclosed |
| US-4556742-A | Process for the preparation of α,δ-diethylenic carbonyl compounds | RHONE-POULENC SANTE (FR) | 1985-12-03 | — | — | US | disclosed |
| EP-0054732-B1 | CONJUGATED POLYPRENYLCARBOXYLIC ACIDS AND THEIR DERIVATIVES AS WELL AS PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS | Eisai Co., Ltd. (JP) | 1984-06-20 | — | — | EP | disclosed |
| EP-0059258-B1 | PHARMACEUTICAL PREPARATIONS COMPRISING POLYPRENYL COMPOUNDS, ESPECIALLY AS ANTI-CANCER AGENTS, AND PHARMACEUTICAL COMPOSITIONS FOR THE PREVENTION AND TREATMENT OF CANCER AND SKIN DISEASES | Eisai Co., Ltd. (JP) | 1984-05-30 | — | — | EP | disclosed |
| EP-0107188-A1 | A pharmaceutical composition and the use thereof for the treatment of inflammation | Eisai Co., Ltd. (JP) | 1984-05-02 | — | — | EP | disclosed |
| JP-S57181012-A | DRUG COMPOSED OF POLYPRENYL COMPOUND | EISAI CO LTD | 1982-11-08 | — | — | JP | disclosed |
| EP-0059258-A1 | Pharmaceutical preparations comprising polyprenyl compounds, especially as anti-cancer agents, and pharmaceutical compositions for the prevention and treatment of cancer and skin diseases | Eisai Co., Ltd. (JP) | 1982-09-08 | — | — | EP | disclosed |
| US-4346109-A | 3,7,11,15-TETRAMETHYL-2,4,6,10,14-HEXADECAPENTAENOIC ACID OR SALT | EISAI CO., LTD. (JP) | 1982-08-24 | — | — | US | disclosed |
| EP-0054732-A1 | Conjugated polyprenylcarboxylic acids and their derivatives as well as pharmaceutical preparations containing these compounds | Eisai Co., Ltd. (JP) | 1982-06-30 | — | — | EP | disclosed |
| JP-S5731615-A | REMEDY FOR SKIN DISEASE WITH KERATINIZATION | EISAI CO LTD | 1982-02-20 | — | — | JP | disclosed |
| US-4122119-A | Process for the production of unsaturated ketones | KURARAY CO., LTD. (JP) | 1978-10-24 | — | — | US | disclosed |
| US-4116955-A | META-CYCLOPHANE AND A TRANS-TERPENOID, SEPARATION OF ISOMERS | TEIJIN LIMITED (JP) | 1978-09-26 | — | — | US | disclosed |