Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21457779 | 0.81 | CYP19A1 (0.47) | CYP3A4CYP3A5CYP19A1POLBKCNA5 | |
| SCHEMBL7614593 | 0.81 | CYP3A4 (0.48) | CYP3A4CYP3A5CYP19A1POLBKCNA5 | |
| SCHEMBL30431325 | 0.81 | CYP19A1 (0.47) | CYP3A4CYP3A5CYP19A1POLBKCNA5 | |
| SCHEMBL24608491 | 0.76 | CYP19A1 (0.50) | CYP3A4CYP3A5CYP19A1CYP11B2CYP1A2 | |
| SCHEMBL11147179 | 0.76 | KCNA5 (0.47) | CYP3A4CYP3A5CYP19A1KCNA5CYP11B2 | |
| SCHEMBL30589181 | 0.76 | CYP19A1 (0.50) | CYP3A4CYP3A5CYP19A1CYP11B2CYP1A2 | |
| SCHEMBL22714972 | 0.73 | CYP19A1 (0.43) | CYP3A4CYP3A5CYP19A1KCNA5CYP11B2 | |
| SCHEMBL29503990 | 0.73 | CYP19A1 (0.43) | CYP3A4CYP3A5CYP19A1KCNA5CYP11B2 | |
| SCHEMBL3235238 | 0.72 | CYP19A1 (0.55) | CYP3A4CYP19A1KCNA5CYP11B2CYP1A2 | |
| SCHEMBL4196221 | 0.72 | CYP19A1 (0.55) | CYP3A4CYP19A1KCNA5CYP11B2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043345-A | Cognition activators; alzheimer's disease | NOVO NORDISK A/S (DK) | 1991-08-27 | — | — | US | disclosed |