Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27609833 | 0.82 | ELANE (0.41) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL2988211 | 0.81 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL2981112 | 0.81 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL1790087 | 0.81 | MAPT (0.51) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL27702602 | 0.79 | ELANE (0.47) | MAPTMEN1KMT2AALDH1A1CYP1A2 | |
| Propionic Acid SCHEMBL27628944 | 0.79 | ELANE (0.47) | MAPTALDH1A1NPC1RAB9AELANE | |
| Methyl Alcohol SCHEMBL28471241 | 0.78 | TDP1 (0.47) | MAPTMEN1KMT2AALDH1A1GAA | |
| SCHEMBL1148890 | 0.78 | — | — | |
| Benzene SCHEMBL7925278 | 0.78 | TDP1 (0.50) | MAPTALDH1A1RAB9AELANEATM | |
| SCHEMBL3302 | 0.78 | TDP1 (0.50) | MAPTALDH1A1RAB9AELANEATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5061786-A | Immunosuppressive agents | GENENTECH, INC. (US) | 1991-10-29 | — | — | US | disclosed |