Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 9/20 | 0.52 |
| ▸ | BACE1 | P56817 | 9/20 | 0.52 |
| ▸ | GABRP | O00591 | 1/20 | 0.47 |
| ▸ | GABRD | O14764 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
| ▸ | GABRE | P78334 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770984 | 1.00 | PTGIR (0.64) | PTGIRKDM4ETSHRHSD17B10MEN1 | |
| SCHEMBL9771000 | 0.86 | KMT2A (0.57) | PTGIRKDM4ETSHRMEN1KMT2A | |
| SCHEMBL9770961 | 0.86 | KMT2A (0.57) | PTGIRKDM4ETSHRMEN1KMT2A | |
| SCHEMBL9771007 | 0.81 | MEN1 (0.51) | PTGIRMEN1KMT2AACHEBACE1 | |
| SCHEMBL9771033 | 0.81 | MEN1 (0.51) | PTGIRMEN1KMT2AACHEBACE1 | |
| SCHEMBL8104458 | 0.81 | PTGIR (0.67) | PTGIRKDM4ETSHRHSD17B10GABRP | |
| SCHEMBL8104410 | 0.81 | PTGIR (0.67) | PTGIRKDM4ETSHRHSD17B10GABRP | |
| SCHEMBL9792907 | 0.79 | PTGIR (0.64) | PTGIRKDM4ETSHRHSD17B10GABRP | |
| SCHEMBL9206357 | 0.78 | PTGIR (1.00) | PTGIRKDM4ETSHRHSD17B10GABRP | |
| SCHEMBL9198869 | 0.78 | PTGIR (1.00) | PTGIRKDM4ETSHRHSD17B10GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442448-A2 | Heterocyclic carboxylic acids and esters | Bristol-Myers Squibb Company (US) | 1991-08-21 | — | — | EP | claimed |
| US-5021415-A | Antithrombogenic agent | BRISTOL-MYERS SQUIBB CO. (US) | 1991-06-04 | — | — | US | claimed |
| EP-0442448-A2 | Heterocyclic carboxylic acids and esters | Bristol-Myers Squibb Company (US) | 1991-08-21 | — | — | EP | disclosed |
| US-5021415-A | Antithrombogenic agent | BRISTOL-MYERS SQUIBB CO. (US) | 1991-06-04 | — | — | US | disclosed |