Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5471181 | 1.00 | AR (0.41) | ARSTAT3LMNAMAPK1DHODH | |
| SCHEMBL5475793 | 1.00 | AR (0.41) | ARSTAT3LMNAMAPK1DHODH | |
| SCHEMBL8423991 | 0.91 | STAT3 (0.44) | STAT3LMNAMAPK1DHODHKMT2A | |
| SCHEMBL9771994 | 0.87 | AR (0.41) | ARLMNAMAPK1ALDH1A1 | |
| SCHEMBL5473721 | 0.87 | STAT3 (0.41) | STAT3LMNAMAPK1DHODHKMT2A | |
| SCHEMBL9772011 | 0.87 | AR (0.41) | ARLMNAMAPK1ALDH1A1 | |
| SCHEMBL5473718 | 0.87 | STAT3 (0.41) | STAT3LMNAMAPK1DHODHKMT2A | |
| SCHEMBL5473716 | 0.87 | STAT3 (0.41) | STAT3LMNAMAPK1DHODHKMT2A | |
| SCHEMBL9691605 | 0.86 | STAT3 (0.39) | STAT3LMNAMAPK1DHODHKMT2A | |
| SCHEMBL9691621 | 0.86 | STAT3 (0.39) | STAT3LMNAMAPK1DHODHKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032523-A | Preparation of optically active esters | LION CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |
| EP-0189878-B1 | PROCESS FOR PREPARING OPTICALLY ACTIVE GLYCEROL DERIVATES | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1991-07-10 | — | — | EP | disclosed |
| US-4863859-A | BIOCHEMICAL RESOLUTION USING AN ESTERASE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0189878-A2 | Process for preparing optically active glycerol derivates | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | disclosed |