Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | YAP1 | P46937 | 1/20 | 0.33 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9772004 | 1.00 | POLB (0.38) | POLBMAPK1STAT3ALDH1A1HTT | |
| SCHEMBL9772016 | 1.00 | POLB (0.38) | POLBMAPK1STAT3ALDH1A1HTT | |
| SCHEMBL9691605 | 0.90 | STAT3 (0.39) | POLBMAPK1STAT3ALDH1A1GAA | |
| SCHEMBL9691621 | 0.90 | STAT3 (0.39) | POLBMAPK1STAT3ALDH1A1GAA | |
| SCHEMBL9626304 | 0.90 | POLB (0.39) | POLBMAPK1STAT3ALDH1A1HTT | |
| SCHEMBL9626295 | 0.90 | POLB (0.39) | POLBMAPK1STAT3ALDH1A1HTT | |
| SCHEMBL9626924 | 0.85 | PLA2G2C (0.40) | POLBMAPK1STAT3ALDH1A1HTT | |
| SCHEMBL9626931 | 0.85 | PLA2G2C (0.40) | POLBMAPK1STAT3ALDH1A1HTT | |
| SCHEMBL9625708 | 0.84 | PLA2G2C (0.42) | MAPK1ALDH1A1KMT2ALMNA | |
| SCHEMBL9625700 | 0.84 | PLA2G2C (0.42) | MAPK1ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032523-A | Preparation of optically active esters | LION CORPORATION (JP) | 1991-07-16 | — | — | US | disclosed |
| US-4863859-A | BIOCHEMICAL RESOLUTION USING AN ESTERASE | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-09-05 | — | — | US | disclosed |
| EP-0189878-A2 | Process for preparing optically active glycerol derivates | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | disclosed |