Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1468464 | 0.73 | SMN1; SMN2 (0.31) | SMN1; SMN2HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL988375 | 0.70 | PTGS1 (0.39) | SMN1; SMN2HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL11615938 | 0.68 | PTGS1 (0.38) | SMN1; SMN2HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL4119359 | 0.67 | KMT2A (0.36) | SMN1; SMN2HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL2919621 | 0.65 | HDAC4 (0.39) | SMN1; SMN2HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL28290161 | 0.65 | EPHX1 (0.37) | SMN1; SMN2HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL3526537 | 0.65 | — | — | |
| SCHEMBL953641 | 0.65 | — | — | |
| SCHEMBL3901052 | 0.65 | — | — | |
| SCHEMBL3317982 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992429-A | Novel HMG-COA reductase inhibitors | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1991-02-12 | — | — | US | disclosed |