SCHEMBL9773161

SCHEMBL9773161

CCCCCCCCOC(=O)[C@@H]1C[C@@H]2CCC[C@@H]2N1C(=O)[C@H](C)N[C@@H](CCc1ccccc1)C(=O)OCC

nearest known ligand 0.77

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ACE P12821 14/20 0.77
MEN1 O00255 2/20 0.77
KMT2A Q03164 2/20 0.77
CYP3A4 P08684 1/20 0.77
ALOX15 P16050 1/20 0.77
LMNA P02545 2/20 0.75
USP2 O75604 1/20 0.75
SMN1; SMN2 Q16637 1/20 0.51
ABCB11 O95342 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9775447 1.00 ACE (0.77) ACEMEN1KMT2ACYP3A4ALOX15
SCHEMBL9775445 1.00 ACE (0.77) ACEMEN1KMT2ACYP3A4ALOX15
SCHEMBL9773163 1.00 ACE (0.77) ACEMEN1KMT2ACYP3A4ALOX15
SCHEMBL9773146 1.00 ACE (0.77) ACEMEN1KMT2ACYP3A4ALOX15
SCHEMBL9773120 1.00 ACE (0.77) ACEMEN1KMT2ACYP3A4ALOX15
SCHEMBL9775474 1.00 ACE (0.77) ACEMEN1KMT2ACYP3A4ALOX15
SCHEMBL9593609 1.00 ACE (0.77) ACEMEN1KMT2ACYP3A4ALOX15
SCHEMBL9773138 1.00 ACE (0.77) ACEMEN1KMT2ACYP3A4ALOX15
SCHEMBL9773238 1.00 ACE (0.77) ACEMEN1KMT2ACYP3A4ALOX15
SCHEMBL9773177 0.98 ACE (0.73) ACEMEN1KMT2ACYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5043346-A Amino acid esters, pharmaceuticals containing them, and the use thereof in learning disorders HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-27 US claimed
US-12453717-B1 Methods of treating symptoms of coronavirus infection with viral protease inhibitors Accencio LC (US) 2025-10-28 US disclosed
US-5043346-A Amino acid esters, pharmaceuticals containing them, and the use thereof in learning disorders HOECHST AKTIENGESELLSCHAFT (DE) 1991-08-27 US disclosed
US-4999370-A ANXIOLYTIC AGENTS, INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME, NOOTROPIC AGENTS HOECHST AKTIENGESELLSCHAFT (DE) 1991-03-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12453717-B1 Methods of treating symptoms of coronavirus infection with viral protease inhibitors ACE, ACE2, TMPRSS2 ACE 1/4885MEN1 4436/4885KMT2A 708/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.