Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ACE | P12821 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1858577 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2ACEMAPTTAAR1THRB | |
| SCHEMBL5674353 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2ACEMAPTTAAR1THRB | |
| SCHEMBL10957115 | 0.90 | KMT2A (0.39) | SMN1; SMN2ACEMAPTHTTHSD17B10 | |
| SCHEMBL7722450 | 0.89 | SMN1; SMN2 (0.48) | SMN1; SMN2ACEMAPTMMP8PPARG | |
| SCHEMBL20676404 | 0.89 | ACE (0.37) | SMN1; SMN2ACEMAPTHTTHSD17B10 | |
| SCHEMBL7375987 | 0.88 | BLM (0.41) | BLMPPARGPPARAL3MBTL1 | |
| SCHEMBL5012826 | 0.88 | BLM (0.41) | BLMPPARGPPARAL3MBTL1 | |
| SCHEMBL8142297 | 0.88 | MEN1 (0.43) | SMN1; SMN2BLMPPARGPPARA | |
| SCHEMBL7344531 | 0.88 | BLM (0.41) | BLMPPARGPPARAL3MBTL1 | |
| SCHEMBL7728941 | 0.88 | MEN1 (0.43) | SMN1; SMN2BLMPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5043346-A | Amino acid esters, pharmaceuticals containing them, and the use thereof in learning disorders | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-08-27 | — | — | US | disclosed |