Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.51 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.51 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.51 |
| ▸ | FAP | Q12884 | 1/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.51 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14376836 | 0.82 | DPP4 (0.55) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL13226101 | 0.82 | DPP4 (0.55) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL9022137 | 0.81 | DPP4 (0.54) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL9022144 | 0.81 | DPP4 (0.54) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL30924754 | 0.78 | DPP4 (0.60) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL29565533 | 0.78 | DPP4 (0.60) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL27902671 | 0.78 | DPP4 (0.60) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL825679 | 0.78 | DPP4 (0.60) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL6371844 | 0.78 | DPP4 (0.60) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL29356868 | 0.78 | DPP4 (0.60) | DPP4DPP8DPP9FAPDPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4983623-A | Prolyl endopeptidase inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-08 | — | — | US | disclosed |
| EP-0320753-A2 | Derivatives of cyclic aminoacids, their preparation, compounds containing them, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-06-21 | — | — | EP | disclosed |