Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | FKBP1A | P62942 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775244 | 0.88 | ACE (0.56) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9775237 | 0.88 | ACE (0.56) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9775259 | 0.87 | ACE (0.51) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9773177 | 0.85 | ACE (0.73) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9773185 | 0.85 | ACE (0.68) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9773136 | 0.85 | ACE (0.68) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9775452 | 0.85 | ACE (0.68) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9773206 | 0.85 | ACE (0.73) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9775448 | 0.85 | ACE (0.60) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9773138 | 0.85 | ACE (0.77) | ACEMEN1KMT2ACYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5068242-A | PYRROLIDINE-2-CARBOXYLIC ACID DERIVATIVES AND THEIR USE FOR PSYCHOTROPIC ACTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-11-26 | — | — | US | disclosed |