SCHEMBL977527

SCHEMBL977527

C=C(C)C(=O)OCC(C)C[Si](C)(OC)OC

nearest known ligand 0.55

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.55
ALDH1A1 P00352 2/20 0.38
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2772530 0.87 TSHR (0.55) TSHRALDH1A1THRB
SCHEMBL9301359 0.85 TSHR (0.53) TSHRALDH1A1THRB
SCHEMBL975918 0.85 TSHR (0.53) TSHRALDH1A1THRB
SCHEMBL615161 0.85 TSHR (0.56) TSHRALDH1A1THRB
SCHEMBL2772659 0.84 TSHR (0.51) TSHRALDH1A1THRB
SCHEMBL4595250 0.82 TSHR (0.43) TSHRALDH1A1THRB
SCHEMBL3319370 0.80 TSHR (0.75) TSHRALDH1A1THRB
SCHEMBL2334126 0.79 TSHR (0.58) TSHRALDH1A1THRB
SCHEMBL9301563 0.79 TSHR (0.53) TSHRALDH1A1THRB
SCHEMBL9302380 0.79 TSHR (0.53) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1417209-B1 HIGH BOILING INHIBITORS FOR DISTILLABLE, POLYMERIZABLE MONOMERS CROMPTON CORP (US) 2008-01-16 EP claimed
EP-1417209-A1 HIGH BOILING INHIBITORS FOR DISTILLABLE, POLYMERIZABLE MONOMERS Crompton Corporation (US) 2004-05-12 EP claimed
WO-2003014130-A1 HIGH BOILING INHIBITORS FOR DISTILLABLE, POLYMERIZABLE MONOMERS CROMPTON CORPORATION (US) 2003-02-20 WO claimed
US-6475347-B1 High boiling inhibitors for distillable, polymerizable monomers CROMPTON CORPORATION 2002-11-05 US claimed
CN-101405315-B Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG 2011-04-13 CN disclosed
US-7867619-B2 Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG (CH) 2011-01-11 US disclosed
US-7851562-B2 Water-soluble silicon-containing polymer, making method, coating composition, and coated article SHIN-ETSU CHEMICAL CO., LTD. (JP) 2010-12-14 US disclosed
EP-1925627-B1 Water-soluble silicon-containing polymer, making method, coating composition, and coated article SHINETSU CHEMICAL CO (JP) 2010-04-28 EP disclosed
EP-1981924-B1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES SIKA TECHNOLOGY AG (CH) 2010-03-31 EP disclosed
US-20090214879-A1 Moisture-Curing Compositions Containing Silane-Functional Polymers With Good Adhesive Properties SIKA TECHNOLOGY AG (CH) 2009-08-27 US disclosed
CN-101405315-A Moisture-curing compositions containing silane-functional polymers with good adhesive properties SIKA TECHNOLOGY AG (CH) 2009-04-08 CN disclosed
EP-1981924-A1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES Sika Technology AG (CH) 2008-10-22 EP disclosed
US-20080132652-A1 WATER-SOLUBLE SILICON-CONTAINING POLYMER, MAKING METHOD, COATING COMPOSITION, AND COATED ARTICLE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-06-05 US disclosed
EP-1925627-A1 Water-soluble silicon-containing polymer, making method, coating composition, and coated article Shin-Etsu Chemical Co., Ltd. (JP) 2008-05-28 EP disclosed
EP-1417209-B1 HIGH BOILING INHIBITORS FOR DISTILLABLE, POLYMERIZABLE MONOMERS CROMPTON CORP (US) 2008-01-16 EP disclosed
WO-2007085620-A1 MOISTURE-CURING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS WITH GOOD ADHESIVE PROPERTIES SIKA TECHNOLOGY AG (CH) 2007-08-02 WO disclosed
EP-1417209-A1 HIGH BOILING INHIBITORS FOR DISTILLABLE, POLYMERIZABLE MONOMERS Crompton Corporation (US) 2004-05-12 EP disclosed
US-20030065177-A1 High boiling inhibitors for distillable, polymerizable monomers CROMPTON CORPORATION, A CORPORATION OF THE STATE OF DELAWARE 2003-04-03 US disclosed
WO-2003014130-A1 HIGH BOILING INHIBITORS FOR DISTILLABLE, POLYMERIZABLE MONOMERS CROMPTON CORPORATION (US) 2003-02-20 WO disclosed
US-6475347-B1 High boiling inhibitors for distillable, polymerizable monomers CROMPTON CORPORATION 2002-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065177-A1 High boiling inhibitors for distillable, polymerizable monomers ROS1, POLR1A, ACP1 TSHR 4270/4885ALDH1A1 1573/4885THRB 3296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.