Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429359 | 0.97 | — | — | |
| SCHEMBL2231712 | 0.92 | TSHR (0.43) | TSHR | |
| SCHEMBL28671408 | 0.87 | TSHR (0.44) | TSHRTDP1ALDH1A1MAPK1 | |
| SCHEMBL3623070 | 0.87 | TSHR (0.44) | TSHRTDP1ALDH1A1MAPK1 | |
| SCHEMBL30912803 | 0.87 | TSHR (0.44) | TSHR | |
| SCHEMBL8038622 | 0.84 | TSHR (0.36) | TSHR | |
| SCHEMBL619867 | 0.84 | TSHR (0.47) | TSHRALDH1A1 | |
| SCHEMBL29093233 | 0.84 | TSHR (0.47) | TSHRALDH1A1 | |
| SCHEMBL428320 | 0.84 | TSHR (0.47) | TSHRALDH1A1 | |
| SCHEMBL29093054 | 0.84 | TSHR (0.47) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059694-A | 3-SUBSTITUTED POLYPYRROLE | NIPPON OIL CO., LTD. (JP) | 1991-10-22 | — | — | US | disclosed |
| US-4156603-A | COMPLEXED WITH A POLYFUNCTIONAL LEWIS BASE | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-05-29 | — | — | US | disclosed |
| US-4147530-A | Reductions of inorganic substrates with chelated sodium hydridoaluminates or hydridoborates | EXXON RESEARCH & ENGINEERING CO. (US) | 1979-04-03 | — | — | US | disclosed |
| US-4088666-A | Reductions with chelated lithium hydridoaluminates or hydridoborates | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-05-09 | — | — | US | disclosed |