Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891479 | 0.84 | TSHR (0.57) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL23494022 | 0.83 | TSHR (0.60) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL31059272 | 0.82 | TSHR (0.69) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL29362562 | 0.81 | TSHR (0.67) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL15243937 | 0.81 | TSHR (0.67) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL35200 | 0.81 | TSHR (0.67) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11746726 | 0.79 | TSHR (0.70) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL18123454 | 0.79 | TSHR (0.63) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL8965855 | 0.78 | TSHR (0.75) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL27807065 | 0.77 | TSHR (0.61) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4999218-A | (Meth)acrylate copolymer and aromatic ketone dispersion; concrete roof tiles | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |