Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.55 |
| ▸ | RARA | P10276 | 2/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399117 | 0.99 | RARB (0.53) | RARBRARARARGSMN1; SMN2MAPT | |
| SCHEMBL9398914 | 0.92 | RARB (0.54) | RARBRARARARGSMN1; SMN2MAPT | |
| SCHEMBL9398769 | 0.91 | RARB (0.49) | RARBRARARARGSMN1; SMN2MAPT | |
| SCHEMBL9399379 | 0.91 | RARB (0.52) | RARBRARARARGSMN1; SMN2MAPT | |
| SCHEMBL9399825 | 0.89 | RARB (0.49) | RARBRARARARGSMN1; SMN2MAPT | |
| SCHEMBL10551425 | 0.88 | RARB (0.57) | RARBRARARARGSMN1; SMN2MAPT | |
| SCHEMBL10549824 | 0.88 | RARB (0.57) | RARBRARARARGSMN1; SMN2MAPT | |
| SCHEMBL9817558 | 0.88 | RARB (0.57) | RARBRARARARGSMN1; SMN2MAPT | |
| SCHEMBL10572481 | 0.87 | RARB (0.51) | RARBRARARARGSMN1; SMN2MAPT | |
| SCHEMBL10572431 | 0.87 | RARB (0.51) | RARBRARARARGSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047170-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1991-09-10 | — | — | US | disclosed |