Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | VDR | P11473 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399336 | 0.86 | MAPT (0.38) | CNR2CNR1GAAMAPT | |
| SCHEMBL9398691 | 0.85 | RARB (0.37) | CNR2CNR1GAAMAPT | |
| SCHEMBL9398830 | 0.84 | MAPT (0.37) | CNR2CNR1GAAMAPT | |
| SCHEMBL9399877 | 0.84 | OPRL1 (0.41) | CNR2CNR1GAAMAPT | |
| SCHEMBL9399524 | 0.83 | CNR2 (0.43) | CNR2TLR7AR | |
| SCHEMBL9398933 | 0.83 | CYP3A4 (0.37) | CNR2TLR7ARVDR | |
| SCHEMBL9399626 | 0.82 | CYP3A4 (0.39) | CNR2TLR7ARVDR | |
| SCHEMBL9399309 | 0.82 | CNR2 (0.43) | CNR2TLR7ARGAAMAPT | |
| SCHEMBL9399384 | 0.80 | SPHK1 (0.35) | MAPT | |
| SCHEMBL9399715 | 0.80 | CNR2 (0.46) | CNR2TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047170-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4808333-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1989-02-28 | — | — | US | disclosed |
| EP-0084194-B1 | LIQUID CRYSTAL MIXTURES | MERCK PATENT GmbH (DE) | 1986-04-30 | — | — | EP | disclosed |
| EP-0084194-A1 | Liquid crystal mixtures | MERCK PATENT GmbH (DE) | 1983-07-27 | — | — | EP | disclosed |