Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | RARG | P13631 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9399702 | 0.99 | RARB (0.45) | RARBRAB9ASMN1; SMN2HSD17B10MAPT | |
| SCHEMBL9399674 | 0.96 | RARB (0.51) | RARBRAB9ASMN1; SMN2HSD17B10MAPT | |
| SCHEMBL9399246 | 0.94 | RARB (0.49) | RARBRAB9ASMN1; SMN2HSD17B10MAPT | |
| SCHEMBL9399660 | 0.92 | RARB (0.50) | RARBRAB9ASMN1; SMN2HSD17B10MAPT | |
| SCHEMBL9398841 | 0.90 | NPC1 (0.43) | RARBRAB9ASMN1; SMN2HSD17B10NPC1 | |
| SCHEMBL9399921 | 0.83 | RARB (0.52) | RARBRAB9ASMN1; SMN2HSD17B10MAPT | |
| SCHEMBL10463240 | 0.82 | RARB (0.49) | RARBRAB9ASMN1; SMN2HSD17B10MAPT | |
| SCHEMBL10460834 | 0.82 | RARB (0.49) | RARBRAB9ASMN1; SMN2HSD17B10MAPT | |
| SCHEMBL10462098 | 0.82 | RARB (0.49) | RARBRAB9ASMN1; SMN2HSD17B10MAPT | |
| SCHEMBL10978750 | 0.81 | RARB (0.67) | RARBRAB9ASMN1; SMN2HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047170-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1991-09-10 | — | — | US | disclosed |