Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.48 |
| ▸ | RARB | P10826 | 1/20 | 0.47 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775763 | 1.00 | SPHK1 (0.48) | SPHK1RARBSPHK2CYP3A4CYP2C9 | |
| SCHEMBL10946817 | 0.97 | SPHK1 (0.47) | SPHK1RARBSPHK2CYP3A4CYP2C9 | |
| SCHEMBL10946823 | 0.97 | SPHK1 (0.47) | SPHK1RARBSPHK2CYP3A4CYP2C9 | |
| SCHEMBL10943958 | 0.95 | SPHK1 (0.42) | SPHK1RARBSPHK2CYP3A4CYP2C9 | |
| SCHEMBL10943945 | 0.95 | SPHK1 (0.42) | SPHK1RARBSPHK2CYP3A4CYP2C9 | |
| SCHEMBL10947793 | 0.94 | SPHK1 (0.50) | SPHK1RARBSPHK2CYP3A4CYP2C9 | |
| SCHEMBL10947782 | 0.94 | SPHK1 (0.50) | SPHK1RARBSPHK2CYP3A4CYP2C9 | |
| SCHEMBL10947235 | 0.94 | SPHK1 (0.43) | SPHK1RARBSPHK2CYP3A4CYP2C9 | |
| SCHEMBL10947243 | 0.94 | SPHK1 (0.43) | SPHK1RARBSPHK2CYP3A4CYP2C9 | |
| SCHEMBL10945641 | 0.93 | RARB (0.50) | SPHK1RARBSPHK2FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047170-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1991-09-10 | — | — | US | disclosed |
| US-4808333-A | Anisotropic compounds having nematic phase and liquid crystal mixtures | MERCK PATENT GMBH (DE) | 1989-02-28 | — | — | US | disclosed |
| US-4545922-A | Liquid crystalline fluorine-containing cyclohexylbiphenyls and dielectrics and electro-optical display elements based thereon | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-10-08 | — | — | US | disclosed |
| EP-0051738-B1 | CYCLOHEXYL-BIPHENYL DERIVATIVES THAT CONTAIN FLUOR, DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL INDICATING ELEMENT | MERCK PATENT GmbH (DE) | 1984-07-25 | — | — | EP | disclosed |
| US-4415470-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1983-11-15 | — | — | US | disclosed |