Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21310428 | 1.00 | HSD17B10 (0.58) | HSD17B10CYP3A4TDP1TAAR1ESR1 | |
| SCHEMBL26567857 | 0.91 | TDP1 (0.48) | HSD17B10CYP3A4TDP1TAAR1ESR1 | |
| SCHEMBL3278733 | 0.86 | ESR1 (0.62) | HSD17B10TDP1ESR1ESR2MAPK1 | |
| SCHEMBL807664 | 0.81 | CYP3A4 (0.78) | HSD17B10CYP3A4TDP1TAAR1NPC1 | |
| SCHEMBL13310879 | 0.81 | CYP3A4 (0.78) | HSD17B10CYP3A4TDP1TAAR1NPC1 | |
| SCHEMBL20323054 | 0.81 | CYP3A4 (0.78) | HSD17B10CYP3A4TDP1TAAR1NPC1 | |
| SCHEMBL7624177 | 0.80 | ESR1 (0.52) | HSD17B10TDP1ESR1ESR2MAPK1 | |
| SCHEMBL28595339 | 0.80 | ESR1 (0.52) | HSD17B10TDP1ESR1ESR2MAPK1 | |
| SCHEMBL16578789 | 0.79 | SERPINE1 (0.56) | HSD17B10CYP3A4TDP1TAAR1ESR1 | |
| SCHEMBL24524183 | 0.75 | CYP3A4 (1.00) | HSD17B10CYP3A4TDP1TAAR1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3247623-A | — | — | None | — | — | JP | disclosed |
| JP-2237972-A | — | — | None | — | — | JP | disclosed |
| JP-H03247623-A | POLYIMIDE RESIN AND ITS PREPARATION | IMAI YOSHIO | 1991-11-05 | — | — | JP | disclosed |
| JP-H02237972-A | AROMATIC DIAMINE COMPOUND AND ITS PRODUCTION | IMAI YOSHIO | 1990-09-20 | — | — | JP | disclosed |