Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | DHFR | P00374 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL521907 | 0.82 | MAPT (0.72) | MAPTSMN1; SMN2POLBRAB9ALMNA | |
| SCHEMBL29435521 | 0.81 | MAPT (0.97) | MAPTSMN1; SMN2POLBRAB9ALMNA | |
| SCHEMBL15141576 | 0.81 | MAPT (0.97) | MAPTSMN1; SMN2POLBRAB9ALMNA | |
| SCHEMBL3539759 | 0.81 | MAPT (0.90) | MAPTSMN1; SMN2POLBRAB9ALMNA | |
| SCHEMBL29437404 | 0.80 | POLB (1.00) | MAPTSMN1; SMN2POLBRAB9ACHRNB2 | |
| SCHEMBL521371 | 0.80 | POLB (1.00) | MAPTSMN1; SMN2POLBRAB9ACHRNB2 | |
| SCHEMBL17631619 | 0.80 | MAPT (0.66) | MAPTSMN1; SMN2POLBRAB9ACHRNB2 | |
| SCHEMBL30513226 | 0.80 | MAPT (0.66) | MAPTSMN1; SMN2POLBRAB9ACHRNB2 | |
| SCHEMBL29437410 | 0.79 | MAPT (1.00) | MAPTSMN1; SMN2POLBRAB9ALMNA | |
| SCHEMBL2722856 | 0.79 | MAPT (1.00) | MAPTSMN1; SMN2POLBRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023258-A | Triazole antifungal agents | PFIZER INC. (US) | 1991-06-11 | — | — | US | disclosed |
| EP-0352946-A1 | Triazole antifungal agents | Pfizer Limited (GB) | 1990-01-31 | — | — | EP | disclosed |